Corneal cross-linking for ectasia started in 1998 with the «Dresden Protocol» for epi-off CXL. The video features Prof. Frederik Raiskup from the University Eye Clinic Dresden who explains the origins of the “Dresden Protocol”, currently Protocol 1 in the C-Eye device .
Ever since the discovery of oxygen as an essential element in the CXL process by Farhad Hafezi’s research group at the University of Zurich, the field has developed substantially: accelerated protocols have been developed to save on treatment time, transepithelial approaches preserve the epithelium, and pulsed treatment help improve oxygen availability.
For a complete overview of the protocols, see the 2nd edition of the most complete textbook on corneal cross-linking to date:
Another successful clinical study on the effect of PACK-CXL on infectious keratitis from Dr. Rosario Gulias-Cañizo from Mexico:. The body of evidence is steadily increasing, see here: pubmed.ncbi.nlm.nih.gov/33376299/ #cornealulcer #keratitis #CornealCrossLinking #cornea ... See MoreSee Less