Scientific articles

The science behind CXL and PACK-CXL

The Antibacterial Efficacy of High-Fluence PACK Cross-Linking Can Be Accelerated

The Antibacterial Efficacy of High-Fluence PACK Cross-Linking Can Be Accelerated

The article by Lu et al. reports an in vitro study, conducted to determine whether high-fluence…

Does CXL at the slit lamp affect demarcation line depth?

Does CXL at the slit lamp affect demarcation line depth?

The advantages of performing corneal cross-linking (CXL) at the slit lamp are well established.…

Keeping the Cornea Hydrated during CXL: Riboflavin or PBS?

Keeping the Cornea Hydrated during CXL: Riboflavin or PBS?

It has been quite the debate. Should surgeons drop riboflavin onto the cornea during…

Keratoconus and Down Syndrome

Keratoconus and Down Syndrome

Keratoconus and Down Syndrome: How effective is CXL at treating KC in Down Syndrome?…

Corneal Cross-linking in Thin Corneas: From Origins to State of the Art

Corneal Cross-linking in Thin Corneas: From Origins to State of the Art

Our latest review on "CXL in thin corneas". It describes all current approaches how…

High fluence PACK-CXL is better than low fluence PACK-CXL

High fluence PACK-CXL is better than low fluence PACK-CXL

High fluence PACK-CXL has progressed a great deal since it was first developed (1)…

Farhad Hafezi is the world’s top ranked author in CXL

Farhad Hafezi is the world’s top ranked author in CXL

A literature analysis that showed that Farhad Hafezi is the world's top ranked author…

Landmark PACK-CXL trial published

Landmark PACK-CXL trial published

Today, a landmark PACK-CXL trial was published that shows that PACK-CXL is an effective…

PACK-CXL as an Adjuvant Therapy Improves Clinical Outcomes in Keratitis

PACK-CXL as an Adjuvant Therapy Improves Clinical Outcomes in Keratitis

PACK-CXL is safe for use in bacterial keratitis cases. It also seems to add…

What’s the best way to cross-link the eyes of wheelchair users?

What’s the best way to cross-link the eyes of wheelchair users?

It can be challenging to cross-link the eyes of wheelchair users – for the…

Accelerated CXL, without compromising strengthening

Accelerated CXL, without compromising strengthening

Accelerated CXL - but without trading off strength? ELZA researchers have developed a protocol…

US Ophthalmic Review reviews CXL at the Slit Lamp

US Ophthalmic Review reviews CXL at the Slit Lamp

Prof. Hafezi reviews the CXL at the Slit Lamp technique in US Ophthalmic Review

Journal of Refractive Surgery publishes CXL at the Slit Lamp technique

Journal of Refractive Surgery publishes CXL at the Slit Lamp technique

Nikki Hafezi's successful launch of slit lamp cross-linking technology.

Eye rubbing and keratoconus: the forces applied when rubbing eyes

Eye rubbing and keratoconus: the forces applied when rubbing eyes

It’s clear that there is a link between eye rubbing and keratoconus. Eye rubbing can…

Power up! More UV needed to treat IK

Power up! More UV needed to treat IK

PACK-CXL for infectious keratitis is not like treating keratoconus with CXL.

Review on PACK-Crosslinking

Review on PACK-Crosslinking

The most recent and complete overview about this exciting new technology to treat corneal…

PACK-CXL in fungal keratitis

PACK-CXL in fungal keratitis

Article describing the successful use of PACK-CXL as primary therapy in contact lens-related fungal…

Prospective study on PACK-CXL

Prospective study on PACK-CXL

The so far largest study on PACK-CXL for the treatment of advanced corneal ulcers.…

PACK-CXL can be accelerated

PACK-CXL can be accelerated

ELZA research shows that PACK-CXL can be accelerated from 30 minutes to 150 seconds…

Defining PACK-CXL for keratitis

Defining PACK-CXL for keratitis

ELZA members define the new term for cross-linking for corneal infection.

Impact of Fluorescein on PACK-CXL

Impact of Fluorescein on PACK-CXL

Study showing that the eye surgeon must avoid fluorescein staining of a corneal ulcer…

CXL in Bullous Keratopathy, Veterinary Use

CXL in Bullous Keratopathy, Veterinary Use

Scientific study on the value of PACK-CXL for the treatment of bullous keratopathy for…

CXL for Melting Keratitis, Veterinary Use

CXL for Melting Keratitis, Veterinary Use

Case series on the use of PACK-CXL for melting keratitis in the veterinary field.

CXL in Infectious Corneal Melting, Veterinary Use

CXL in Infectious Corneal Melting, Veterinary Use

Scientific study on the value of PACK-CXL for the treatment of infectious and non-infectious…

PACK-CXL to treat Acanthamoeba keratitis

PACK-CXL to treat Acanthamoeba keratitis

ELZA members on the effectiveness of Cross-Linking to treat Acanthamoeba keratitis.

Cross-linking for Infectious Keratitis

Cross-linking for Infectious Keratitis

The very first report on cross-linking for corneal infection.