Medical Advisory Board

Medicine meet science


Prof. Eberhard Spoerl


Prof. Eberhard Spoerl, PhD

Prof. Spoerl, along with Prof. Seiler, is one of the fathers of corneal cross-linking. His physics background, combined with his close collaboration with clinicians and biomedical researchers not only defined cross-linking’s Dresden Protocol, it helped push the field of corneal cross-linking forward into new applications. 

His work has helped the field to continually improve upon the “state of the art”.


Prof. Theo Seiler


Prof. Theo Seiler, MD, PhD

A legendary innovator and pioneer of refractive laser surgery and corneal cross-linking, Prof. Seiler serves as the Chief Medical Officer of the Zurich-based eye clinic, IROC. 

In 2014, the magazine The Ophthalmologist voted Prof. Seiler to the top of the global “PowerList”, a biennial list of the most influential people working in ophthalmology. In 2016 and 2018, he was again voted onto the PowerList.

In addition to his clinical duties, Prof. Seiler is a popular speaker and maintains an intensive international speaking schedule, teaching and instructing the next generation of corneal and refractive surgeons. 

Prof. Paolo Vinciguerra


Prof. Paolo Vinciguerra, MD

The Director of Ophthalmology at Department Istituto Clinico Humanitas and Professor of Ophthalmology at Università degli Studi, Milan, Italy, Prof. Vinciguerra is a pioneer of both photorefractive keratectomy (PRK) and corneal cross-linking surgery, Prof. Vinciguerra is a highly respected leader in the fields of refractive surgery and CXL.

His research work investigating corneal biomechanics and non-invasive methods of assessment has advanced the field considerably, and his longitudinal clinical investigations of both conventional and transepithelial corneal cross-linking has defined our understanding of the efficacy of both approaches.

Prof. Cosimo Mazzotta


Prof. Cosimo Mazzotta, MD, PhD

A trusted surgeon and impactful researcher, Prof. Mazzota is one of the founders of the “Siena Cross-Linking Center” at the University of Siena in Italy. 

Prof. Mazzotta is known for challenging the latest methods and applications of corneal cross-linking to ensure they are safe and effective for his patients and publishing the results for all to see. His particular interest is in corneal confocal microscopy and in optimizing new cross-linking protocols.

Dr. Dr. Emilio Torres


Dr. Dr. Emilio Torres, MD, PhD, FWCRS

Dr. Torres is a double board-certified corneal and cataract/refractive surgeon with an extensive research background.

His numerous contributions have made him one of the most visible clinician-scientists of his generation in the field of corneal degeneration, corneal biomechanics, and refractive surgery. Dr. Torres was awarded several high-impact awards, amongst others the inaugural ICO award in 2021 and the Waring Medal from the ISRS/AAO in 2023.

Prof. Frederik Raiskup


Prof. Frederik Raiskup, MD, PhD

Prof. Raiskup is one of the clinical pioneers of corneal cross-linking, having been a young clinical researcher in Dresden during the early stages of CXL development. 

This means that he has more clinical experience of corneal cross-linking than almost any other surgeon, and his knowledge and experience has made him a popular podium speaker at major international conferences.


Prof. J. Bradley Randleman


Prof. J. Bradley Randleman, MD

An eye surgeon at the internationally renowned Cleveland Clinic, Prof. Randleman’s focus is on clinical research and corneal biomechanics. 

Many know him from the “Randleman score” for corneal ectasia. More recently, he is dedicated to bringing a non-invasive, non-contact method of testing corneal strength, Brillouin microscopy, to market as a means of measuring the effect of corneal cross-linking as on corneal biomechanics – or in other words, the true efficacy of CXL. In 2018, the magazine The Ophthalmologist voted Prof. Randleman onto the PowerList, the list of the most influential ophthalmologists.

Prof. Simon Pot


Prof. Simon Pot, DVM

Prof. Pot is Head of Ophthalmology at the Tierspital, University of Zurich, and leads a research group in the University’s Center for Applied Biotechnology and Molecular Medicine. 

He is an author of many peer-reviewed publications and is considered to be an expert in the fundamentals and clinical applications of PACK-CXL for the treatment of infectious keratitis in veterinary practice.

Prof. Shihao Chen


Prof. Shihao Chen, MD

Professor Chen is the Director of Refractive Surgery Center of Affiliated Eye Hospital of Wenzhou Medical University, China. He was first person to describe excimer laser ablation rates in cross-linked corneas, something that paved the way for ophthalmic surgeons to use refractive laser surgery to improve visual quality in certain candidate patients who have undergone corneal cross-linking.

An educator who is deeply involved in teaching corneal cross-linking to his Chinese colleagues, and a great advocator of the technique, Professor Shen was also the Chinese language editor of the textbook: Corneal Cross-Linking, First Edition.

Prof. Farhad Hafezi


Prof. Farhad Hafezi, MD, PhD, FARVO

Farhad Hafezi, MD PhD FARVO, is a professor, anterior segment surgeon, and ocular cell biologist. In 2014, 2016, 2018 and 2020 he was voted onto the biennial PowerList100 of “The Ophthalmologist”, a list of the 100 most influential people in ophthalmology.

Combing patient care, research & development, and teaching, Hafezi is a pioneer and key opinion leader of corneal cross-linking (CXL). Hafezi’s work comprises over 190 peer-reviewed articles, letters, reviews and book chapters. He is cited by his peers more than 7.900 times (impact factor:  625, h index: 45).