ELZA-sub400 cross-linking for corneas too thin for standard CXL
A new Die Ophthalmologie review explains ELZA-sub400 cross-linking, an individualised protocol that fits the…
Welcome to EMAGine
The C-Eye platform brings the full spectrum of corneal cross-linking together in one versatile system—from keratoconus, keratoglobus, PMD and ultrathin corneas to PACK-CXL, refractive procedures, and ECO-CAIRS. Designed for seamless treatment at the slit lamp, in the operating room, or under the excimer laser.
Testimonials
Ben-Gurion University of the Negev, Israel
The C-eye device is effective in many ocular conditions as keratoconus, iatrogenic ectasia, infectious keratitis and others. The device [represents an] elegant and very useful technology.
Humanitas University Milano, Italy
The C-eye device is the only device that allows the surgeon to view through the system, so that we have full control of the cornea of the patient during the treatment.
The C-eye is truly a disruptive and innovative device that opens new avenues in therapeutic refractive surgery, as well as in the treatment of Keratoconus and keratitis. I’m incredibly excited about all these possibilities.
University of Siena, Italy
It’s a beautiful device. It’s portable, it’s light, it’s easy to use customizable and provide a wide range of intensities, so you can do the custom cross-linking, any way, perfect….we have the opportunity to use the slit lamp technology in outpatients without the use of an operating theater performing epi-on [CXL] techniques.
The Netherlands
The device is a bliss. I love every aspect of it. Well designed, robust, practical.
University Eye Hospital Dresden, Germany
…what’s great is that you can completely control the whole treatment. …you diagnose … a suspected infectious keratitis, you do the scraping, and you can immediately treat them in one session
Use the C-eye technology with the riboflavin of your choice. The C-eye now is available in a locked and unlocked version.
The unlocked version lets you use any type of riboflavin.*
Uncertain which version to choose? You can always start with the locked device and unlock it at a later stage.
* please note: the use of non CE-marked riboflavin in countries of the European Community is illegal.
Advantages
EMAGine’s C-eye device has speerheaded innovation in corneal cross-linking since its inception in 2020.
Bring CXL to the most remote areas with the C-eye device, Ribo-Ker, and a slit lamp. Use the same device for high-tech customized CXL under the excimer laser.
Reduce time and costs related to CXL, perform epi-on CXL at the slit lamp in any procedure room.
To cover all modern CXL protocols
Beam profile delivers more energy in the corneal periphery
Conveniently treat wheelchair users.
For modern CXL: fits on most slit lamps.
For classic CXL: table mount accessory available.
Choose from a number of preset clinical protocols.
Delivers 3, 9, 15, 18 and 30 mW/cm².
The C-eye device is CE marked for the following indications: keratoconus, ectasia after LASIK/PRK, pellucid marginal degeneration, infectious keratitis, sterile corneal melting, bullous keratopathy. The C-eye is not available for sale in the United States.
Our Partners
Frequent Questions
Use a minor procedure room and remember that every CXL procedure not only enhances biomechanics, but also “sterilizes” the cornea by killing microorganisms. Plus, millions of office-based intravitreal injections have shown no increased infection risk.
Irradiation time is not too long. Current modern protocols are integrated in the C-eye device and treat in as little as 10 minutes (CXL) and 4 minutes (PACK-CXL).
We need 3 elements for successful cross-linking: UV light, oxygen and riboflavin. Both UV light and oxygen do not “care” whether the patient is laying down or sitting. As for riboflavin, published research shows that riboflavin concentration is stable in the upright position for up to 60 minutes - much longer than we need for a CXL treatment.
Offer the patient the comfortable surgeon’s chair with an armrest, and take the time to ensure they are well-adjusted. This ensures maximum comfort for the patient.
Fixation is simple. Use the fixation target on most slit lamps (for retinal exams), and the patient will maintain a steady gaze, as shown here.
See slit lamp CXL step-by-step here or simply use the C-eye for classic CXL in the laying position.
Compatibility
The C-eye device fits to most modern slit lamps. Find here the complete list of compatible slit lamps
Branded supplies
EMAGine is proud to offer Ribo-Ker, our own CE-marked riboflavin. No more confusion with different types of riboflavin: we developed the one-fits-all solution.
Ribo-Ker, our CE-marked riboflavin, is designed as a versatile, all-in-one solution, suitable for all CXL* and PACK-CXL techniques.
* epi-on CXL requires additional penetration enhancers
Blog & News
A new Die Ophthalmologie review explains ELZA-sub400 cross-linking, an individualised protocol that fits the…
ELZA researchers report 12-month outcomes for a second-generation sub400 cross-linking protocol that extends CXL…
A new ELZA review in Die Ophthalmologie examines the mechanisms, clinical evidence, protocol selection,…
EMAGine’s CXL technology can be found at CSO Italia (B5.416) and Schwind eye-tech solutions (C3.071)
American University of Beirut